Aβ25-35相关论文
目的 观察不同浓度β-淀粉样蛋白(amyloidβ-protein25-35,Aβ25-35)和六味地黄丸含药血清(medicated serum of Liuwei Dihuang Pi......
目的 探究脑衰反应调节蛋白2(CRMP2)过表达及沉默对Aβ25-35诱导SH-SY5Y细胞损伤的影响.方法 将含CRMP2过表达载体、CRMP2空载体、......
Objective To studies of Scutellaria Barbata flavonoids(SBF)on memory impairment and neuronal damages induced by composit......
目的:探讨艾灸治疗阿尔茨海默病(Alzheimers disease,AD)的作用机制.方法:40只15月龄健康雄性SD大鼠,随机分为正常组、模型组、艾灸......
Arginine vasopressin reversed Aβ25-35-induced depression of hippocampal long-term potentiation in ra
The main pathological characteristics of Alzheimers disease (AD) is the high density of senile plaques (SPs) in the brai......
[Glyl4]-Humanin reverses depressive actions of amyloid β-protein fragment 25-35 on long-term potenti
Alzheimers disease (AD) is the most prevalent neurodegenerative disease in aged people leading to progres-sive loss of m......
Study on the induction of in vivo hippocampal long-term depression and its modulation by amyloid β-p
Accumulation and deposition of amyloid-β peptide (Aβ P) in brain areas have been widely believed to play a critical ro......
大豆异黄酮是富含于大豆及其制品中的植物雌激素,可与雌激素受体(ER)结合,表现弱雌激素作用。细胞培养发现大豆异黄酮可保护皮质神......
Behavioral and electrophysiological study on the neuroprotective effects of lixisenatide against Aβ2
Although glucagon-like peptide-1 (GLP-1), an insulin-releasing gut hormone, has been thought as a promising treatment fo......
Aim To study the improvement of docosahexaenoic Acidphosphatidylcholine (DHAPC) on the cognitive deficits of AD rats ind......
Separation and Purification of Nerve Growth Factor from Venom of vipera russelli siamensis and the p
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This study aimed to investigate whether silibinin could improve the learning and memory, and antioxidant abilities of Al......
Brain dysfunction induced by amyloid β25-35 combined with excessive exercise in rats is protected by
Alzheimers disease (AD), a neurodegenerative disease,is seriously threatening the health of the elderly.In recent years,......
目的 探讨富含GABA 的米糠提取物(rice bran extracts,RBE)对Aβ 25-35 致PC12 细胞损伤的影响.方法(1)RBE 处理对PC12 细胞活性的......
An accumulating body of evidence suggests the significance of neuroinflammation with prolonged microglia activation and ......
To confirm the correlation between Kvl.2 expression on microglia and the effects of low-frequency repetitive magnetic st......
阿尔茨海默病(AD)是一种神经退性疾病,其致病机理尚不清楚,但在各种假说中,β-淀粉样蛋白(Aβ)级联假说居主导地位。研究发现Aβ 形成......
目的阿尔茨海默病(AD)是以记忆障碍和学习认知损伤为特征的慢性神经退行性疾病。目前为止,AD的确切发病机制并未完全阐明,主要有β......
Alzheimers disease(AD)is a progressive neurodegenerative disorder,with no effective method for its treatment so far.......
Alzheimers disease(AD)is the most common form of progressive neuro degenerative disease characterized by neuroinflam......
目的研究硒、锌对β淀粉样蛋白(Aβ25-35)诱导胚鼠神经元细胞神经毒性的保护作用。方法将胚鼠神经元细胞用10mol/L Aβ25-35处理,......
目的 探讨原花青素(Procyanidins,PC)对β淀粉样肽25~35(βamyloidpeptide25 -35, Aβ25-35 )诱导PC12细胞凋亡的影响及其机制。......
目的研究异戊酰紫草素对β-淀粉样蛋白(Aβ25-35)诱导的大鼠嗜铬细胞瘤细胞(PC12细胞)损伤的作用及可能的机制。方法将PC12细胞随......
目的 观察β-淀粉样肽(25-35)[β-amyloid peptide (25-35),Aβ25-35]对体外血清饥饿培养PC12细胞的Cyclin D1、CDK4、pRb、E2F1基......
目的 探讨富含γ-氨基丁酸(γ-aminobutyric acid,GABA)的米糠提取物(rice bran extracts,RBE)对Aβ_(25-35)致PC12细胞损伤的影响。方法......
Neuroprotective Effect of Peptides Extracted from Walnut (Juglans Sigilata Dode) Proteins on Aβ25-35
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提要:观察李氏5号方对人神经母细胞瘤株SY5Y的细胞生长情况和对β-淀粉样肽(β—amyloid,Aβ)导致神经毒性的影响,从而在细胞水平上......
【目的】研究海带岩藻多糖(Fucoidan)对Aβ25-35(Amyloidβ)诱导原代皮层神经突起萎缩和神经元凋亡的抑制作用。【方法】以Aβ25-3......
虾青素(Astaxanthin,AX)是广泛存在于海洋动植物体内的一种类胡萝卜素,具有抗肿瘤、增强免疫功能、改善心血管疾病等功能。研究表......
阿尔兹海默病(Alzheimer’s disease,AD)是一种隐匿起病进行性发展,与年龄相关的中枢神经系统退行性疾病。目前全球约有5000万人患......
研究背景阿尔茨海默病(AD)的神经病理学特征包括老年斑、神经原纤维缠结和突触丢失。AD造成的原因至少部分是由β淀粉样蛋白(Aβ)......
阿尔兹海默症是一种渐进性神经退行性疾病,它的主要病理特征是脑实质内β淀粉样蛋白(Aβ)沉积形成的淀粉样斑和细胞内tau蛋白磷酸......
银杏叶聚戊烯醇类化合物(Polyprenols from the Ginkgo biloba leaves,GP)是继银杏黄酮和萜内酯之后在银杏中发现的又一类极具开发......
目的 探讨丁苯酞(NBP)对β淀粉样蛋白(Aβ)诱导的PC12细胞凋亡的保护作用及其机制.方法 不同浓度的NBP(0.1、1.0、10、100 μmol/L......
目的:探讨石菖蒲、远志的有效成分β-细辛醚、丁香酚和远志皂苷组合抑制β淀粉样蛋白(Aβ)神经细胞毒性与钙离子相关的保护机制。......
目的:研究中药补肾益智方拆方亚组的含药血清对AD细胞模型生工、分化等方面的影响,探讨该方药物的配伍规律.方法:按补肾益智方具有......
目的探讨五味子乙素对Aβ25-35引起的褐家鼠肾上腺嗜铬瘤细胞PC12细胞毒性的作用,并探讨其可能机制。方法 10、25、50、75、100μm......
目的:优选β-细辛醚,丁香酚和远志皂苷对Aβ25-35诱导的海马神经细胞的保护作用,确定三者最佳配比。方法:采用体外细胞培养的方法,......
目的:研究木通皂苷D对Aβ诱导损伤的PC12细胞修复作用及相关基因表达水平的影响。方法:采用MTT法测定木通皂苷D对Aβ诱导损伤的PC1......
目的 :探讨蜜环菌多糖含药血清对Aβ25-35诱导大鼠肾上腺嗜铬细胞瘤细胞(PC12细胞)损伤保护的作用机制。方法 :在Aβ25-35诱导PC12......
目的研究琐琐葡萄总黄酮(Flavones from Vitis viniferal L,VTF)对Aβ25-35诱导PC12细胞Bax表达的影响。方法体外培养PC12细胞,分......
目的探讨黄芪提取物(EA)对Aβ_(25-35)所致海马神经元损伤的保护作用及其作用机制。方法分离孕18 d的胎鼠的海马神经细胞进行体外......
目的探讨亲环素A(CyPA)对Aβ25-35诱导PC12细胞凋亡及氧化应激损伤的影响。方法先用不同浓度(0.1,1,10,100 nmol/L)的CyPA预处理PC......
研究南岭柞木苷G对β淀粉样蛋白25-35片断(Aβ)诱导的PC12细胞损伤的保护作用.用25 μM聚集状的Aβ建立神经细胞损伤模型,将培养的......
目的:研究Fx对Aβ25-35诱导PC12细胞损伤的抗氧化保护作用。方法:采用Aβ25-35诱导PC12细胞损伤模型,给予Fx化合物预处理后,采用MT......
目的:利用AF64A选择性胆碱能破坏特点和Aβ25-35致淀粉样物质沉积作用,建立一个 能更全面地模拟AD神经病理学和行为学变化的大鼠动......
,Protective effects of compound FLZ on β-amyloid peptide-(25-35)-induced mouse hippocampal injury an
Aim: To study the protective effects of compound FLZ, a novel synthetic analogue of natural squamosamide, on leaing and ......